Milan Bergeron-Brlek
Professeur enseignant
Département
Département des enseignements généraux
Formation
B.Sc. chimie, M.Sc. chimie (UQAM), Ph.D. chimie (Simon Fraser, Burnaby, C.-B.)
Bureau
B-1628
Courriel
Expertises
- Chimie organique
- Chimie des sucres
- Méthodologie de synthèse
- Chimie médicinale
Encadrements
- En codirection avec : Demarquette, Nicole R.
Drug Deliver Systems Based on Pullulan, par Sadeghi Lari,Atefe
Été 2024
Publications
- Michael Meanwell, Gaelen Fehr, Weiwu Ren, Bharanishashank Adluri, Victoria Rose, Johannes Lehmann, Steven M. Silverman, Rozhin Rowshanpour, Christopher Adamson, Milan Bergeron-Brlek, Hayden Foy, Venugopal Rao Challa, Louis-Charles Campeau, Travis Dudding, Robert Britton. 2021 « Diversity-oriented synthesis of glycomimetics ». Communications Chemistry vol. 4 , nº 1
- Manh V. Pham, Milan Bergeron-Brlek, Christian Heinis. 2020 « Synthesis of DNA-encoded disulfide- and thioether-cyclized peptides ». ChemBioChem vol. 21 , nº 4. p. 543-549
- S. S. Kale, M. Bergeron-Brlek, Y. Wu, M. G. Kumar, M. V. Pham, J. Bortoli, J. Vesin, X. D. Kong, J. Franco Machado, K. Deyle, P. Gonschorek, G. Turcatti, L. Cendron, A. Angelini, C. Heinis. 2019 « Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands ». Science Advances vol. 5 , nº 8
- Rodrigo Mendoza-Sanchez, Victoria B. Corless, Q. Nhu N. Nguyen, Milan Bergeron-Brlek, John Frost, Shinya Adachi, Dean J. Tantillo, Andrei K. Yudin. 2017 « Cyclols revisited: Facile synthesis of medium-sized cyclic peptides ». Chemistry - A European Journal vol. 23 , nº 54. p. 13319-13322
- Milan Bergeron-Brlek, Jake Goodwin-Tindall, Nevena Cekic, Christian Roth, Wesley F. Zandberg, Xiaoyang Shan, Vimal Varghese, Sherry Chan, Gideon J. Davies, David J. Vocadlo, Robert Britton. 2015 « A convenient approach to stereoisomeric iminocyclitols: Generation of potent brain-permeable OGA inhibitors ». Angewandte Chemie - International Edition vol. 54 , nº 51. p. 15429-15433
- Milan Bergeron-Brlek, Michael Meanwell, Robert Britton. 2015 « Direct synthesis of imino-C-nucleoside analogues and other biologically active iminosugars ». Nature Communications vol. 6
- Milan Bergeron-Brlek, Timothy Teoh, Robert Britton. 2013 « A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis ». Organic Letters vol. 15 , nº 14. p. 3554-3557
- Virgil Percec, Pawaret Leowanawat, Hao-Jan Sun, Oleg Kulikov, Christopher D. Nusbaum, Tam M. Tran, Annabelle Bertin, Daniela A. Wilson, Mihai Peterca, Shaodong Zhang, Neha P. Kamat, Kevin Vargo, Diana Moock, Eric D. Johnston, Daniel A. Hammer, Darrin J. Pochan, Yingchao Chen, Yoann M. Chabre, Tze C. Shiao, Milan Bergeron-Brlek, Sabine André, René Roy, Hans- J. Gabius, Paul A. Heiney. 2013 « Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins ». Journal of the American Chemical Society vol. 135 , nº 24. p. 9055-9077
- Zena Qadoumi, James Senior, Milan Bergeron-Brlek, Robert Britton. 2013 « Direct access to iminosugars through an interrupted kondrat'eva reaction ». Synlett vol. 24 , nº 18. p. 2427-2430
- Sabine André, F. Javier Cañada, Tze Chieh Shiao, Laura Largartera, Tammo Diercks, Milan Bergeron-Brlek, Khouzaima el Biari, Alex Papadopoulos, Joao P. Ribeiro, Mohamed Touaibia, Dolores Solís, Margarita Menéndez, Jesús Jiménez-Barbero, René Roy, Hans-Joachim Gabius. 2012 « Fluorinated carbohydrates as lectin ligands: Biorelevant sensors with capacity to monitor anomer affinity in 19F-NMR-based inhibitor screening ». European Journal of Organic Chemistry vol. 2012 , nº 23. p. 4354-4364
- Milan Bergeron-Brlek, Denis Giguère, Tze Chieh Shiao, Catherine Saucier, René Roy. 2012 « Palladium-catalyzed ullmann-type reductive homocoupling of iodoaryl glycosides ». Journal of Organic Chemistry vol. 77 , nº 6. p. 2971-2977
- Milan Bergeron-Brlek, Tze Chieh Shiao, M. Corazon Trono, René Roy. 2011 « Synthesis of a small library of bivalent α-d-mannopyranosides for lectin cross-linking ». Carbohydrate Research vol. 346 , nº 12. p. 1479-1489
- Milan Bergeron-Brlek. 2015 « Tandem organocatalytic α-chlorination−aldol reactions: A powerful tool for carbohydrate and iminosugars synthesis ». 286 p.Thèse de doctorat. Vancouver, Simon Fraser University.
- Milan Bergeron-Brlek. 2012 « Synthèse de glycosides bivalents biologiquement actifs ». 186 p.Mémoire de maîtrise. Montréal, Université du Québec à Montréal.